Validation of the Brazilian version of the hepatitis B quality of life evaluation instrument - HBQOL, and its application to patients with chronic hepatitis B in Cascavel - PR

The objective of this study is to validate the specific questionnaire for Hepatitis B HBQOL (Hepatitis Quality Life Instrument, version 1.0) Brazilian version, in addition testing its applicability patients with hepatitis under treatment and comparing quality life between using first-line drugs (tenofovir entecavir). For validation, back-translation technique was used a sample 47 patients. Factor analysis performed items each domain internal consistency calculated Cronbach's α coefficient. In assessing validated questionnaire, interviews were carried out 124 Sociodemographic data collected characterize perform correlation analyzes. results demonstrate that successfully validated. among patients, domains psychological well-being stigma obtained highest scores lowest level education conferred better these two domains. comparison tenofovir entecavir showed no significant difference patients' life. use instrument can make therapeutic decisions more rational.